Description

1-[(2,2-Difluoro-1,3-Benzodioxol-5-Yl)-Methyl]Piperazine is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a piperazine ring with a difluorobenzodioxole moiety, making it a versatile intermediate for constructing complex pharmacophores. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atoms can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of novel fluorinated polymers and organic electronic materials with specific optical or electrical properties.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways due to its potential for selective binding.

Basic Information

Product Name	1-[(2,2-Difluoro-1,3-Benzodioxol-5-Yl)-Methyl]Piperazine
CAS No.	1093211-85-8
Molecular Formula	C12H14F2N2O2
Molecular Weight	256.25 g/mol
Synonyms	5-[(Piperazin-1-yl)methyl]-2,2-difluoro-1,3-benzodioxole; 2,2-Difluoro-5-(piperazin-1-ylmethyl)-1,3-benzodioxole; 1-[(2,2-Difluoro-1,3-benzodioxol-5-yl)methyl]piperazine; 1-((2,2-Difluorobenzo[d][1,3]dioxol-5-yl)methyl)piperazine; Difluorobenzodioxole Piperazine Derivative
EINECS	Contact for details

Quality Control

Our 1-[(2,2-Difluoro-1,3-Benzodioxol-5-Yl)-Methyl]Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.