Description

Veledimex (S Enantiomer) is a high-purity, single-enantiomer chemical compound, distinct from its racemic mixture, offering precise biological activity for advanced research and development. This specificity is critical for applications where stereochemistry directly influences efficacy and safety profiles. It is primarily utilized by pharmaceutical researchers, biotechnology companies, and advanced material scientists working on targeted therapeutic platforms and chiral synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs) with defined stereochemistry.
• Proteolysis-Targeting Chimera (PROTAC) Research: Used as a component in the development of heterobifunctional molecules for targeted protein degradation studies.
• Chemical Biology Probe: Acts as a selective ligand or modulator in mechanistic studies of specific biological pathways and protein functions.
• Preclinical Drug Development: Employed in in vitro and in vivo studies to establish proof-of-concept for new therapeutic modalities.
• Chiral Catalyst or Ligand Precursor: Provides a stereochemically pure scaffold for developing asymmetric synthesis catalysts.
• Reference Standard: Used as an analytical standard for method development, validation, and quality control of related compounds.

Basic Information

Product Name	Veledimex (S Enantiomer)
CAS No.	1093131-03-3
Molecular Formula	C20H19F3N2O3
Molecular Weight	392.37 g/mol
Synonyms	(S)-Veledimex; (S)-3-((4-(4-Morpholinyl)phenyl)amino)-5-(trifluoromethyl)-2-pyridinecarboxamide; ARV-110 Component; PROTAC Component; BMS-986142 (S-enantiomer); (S)-BMS-986142; (S)-3-(4-Morpholin-4-yl-phenylamino)-5-trifluoromethyl-pyridine-2-carboxylic acid amide
EINECS	Contact for details

Quality Control

Our Veledimex (S Enantiomer) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and stereochemical purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific project or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.