Description

Veledimex is a potent and selective small molecule ligand for the proprietary GeneSwitch® gene regulation system, widely recognized for its application in advanced biomedical research and therapeutic development. Its high specificity and efficacy make it a critical component for precise temporal control of gene expression in vitro and in vivo. This compound is essential for researchers and developers in the fields of gene therapy, functional genomics, and the creation of next-generation cell-based assays.

Application

• Gene Therapy Research: Used as the activating ligand for the GeneSwitch® system to control therapeutic gene expression in preclinical studies.
• Functional Genomics: Enables inducible gene expression for studying gene function and regulatory networks in cell lines and animal models.
• Cell-Based Assay Development: Facilitates the creation of tightly regulated reporter systems for high-throughput screening and toxicology studies.
• Biopharmaceutical Production: Employed in controlled expression systems for the manufacturing of complex recombinant proteins.
• Oncology Research: Utilized in models to study tumor biology and test inducible gene therapies targeting cancer pathways.
• Neuroscience Studies: Applied in neuronal cell models and animal studies for the temporal analysis of gene function in the nervous system.

Basic Information

Product Name	Veledimex
CAS No.	1093130-72-3
Molecular Formula	C₁₆H₁₄F₃N₃O₂
Molecular Weight	337.30 g/mol
Synonyms	VLD; RTB-1; 4-[(1R)-1-(2,3-Dihydro-1-benzofuran-5-yl)-2,2,2-trifluoroethoxy]-N-[(1S)-1-phenylethyl]-1H-imidazole-2-carboxamide; (R)-4-(1-(Benzofuran-5-yl)-2,2,2-trifluoroethoxy)-N—((S)-1-phenylethyl)-1H-imidazole-2-carboxamide; GeneSwitch® Activator Ligand; Inducible Gene Expression Ligand
EINECS	Contact for details

Quality Control

Our Veledimex is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.