Description

1-(2-Fluoroethyl)Piperazine Dihydrochloride is a high-purity, fluorinated piperazine derivative supplied as a dihydrochloride salt. This compound serves as a critical pharmaceutical intermediate and building block in advanced organic synthesis, enabling the introduction of a fluoroethyl-piperazine moiety into target molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to modulate the physicochemical and pharmacokinetic properties of drug candidates.
• Agrochemical Synthesis: Intermediate in the development of novel herbicides, fungicides, and insecticides that incorporate the fluoroethyl-piperazine functional group.
• Ligand and Chelator Development: Serves as a precursor for creating specialized ligands used in catalysis or diagnostic imaging agents.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme function.
• Custom Synthesis Projects: A versatile starting material for contract research and manufacturing organizations (CROs/CMOs) engaged in custom chemical synthesis.

Basic Information

Product Name	1-(2-Fluoroethyl)Piperazine Dihydrochloride
CAS No.	1089279-64-0
Molecular Formula	C6H14Cl2FN2
Molecular Weight	213.10 g/mol
Synonyms	1-(2-Fluoroethyl)piperazine dihydrochloride; 2-Fluoroethylpiperazine dihydrochloride; N-(2-Fluoroethyl)piperazine dihydrochloride; 1-(2-Fluoroethyl)piperazine hydrochloride (1:2); Piperazine, 1-(2-fluoroethyl)-, dihydrochloride; 1089279-64-0; 1-(2-Fluoro-ethyl)-piperazine dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoroethyl)Piperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.