Description

4-(4-Methanesulfonyl-Phenyl)-Piperidin-4-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its distinct piperidine core functionalized with a methanesulfonylphenyl group. This compound is of significant value in modern medicinal chemistry for its role as a versatile building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) agents and other therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• CNS Drug Development: Integral to the synthesis of potential therapeutics targeting receptors and enzymes within the central nervous system.
• Chemical Synthesis: Serves as a versatile intermediate for further chemical modifications, enabling the creation of diverse compound libraries for high-throughput screening.
• Academic & Contract Research: Employed in university laboratories and CROs (Contract Research Organizations) for exploratory research and custom synthesis projects.

Basic Information

Product Name	4-(4-Methanesulfonyl-Phenyl)-Piperidin-4-Ol
CAS No.	1086392-68-8
Molecular Formula	C13H19NO3S
Molecular Weight	269.36 g/mol
Synonyms	4-(4-Methanesulfonylphenyl)piperidin-4-ol; 4-(4-Methylsulfonylphenyl)-4-piperidinol; 4-Hydroxy-4-(4-methylsulfonylphenyl)piperidine; 4-(4-Methanesulfonylphenyl)-4-hydroxypiperidine; 4-Piperidinol, 4-(4-(methylsulfonyl)phenyl)-; 1086392-68-8; 4-(4-Methylsulphonylphenyl)piperidin-4-ol
EINECS	Contact for details

Quality Control

Our 4-(4-Methanesulfonyl-Phenyl)-Piperidin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (HPLC), related substances, and residual solvents. Our quality commitment supports compliance with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.