Description

2-Bromo-5-(Tetrahydro-Furan-3-Yloxy)Pyrazine is a high-purity, functionalized pyrazine derivative designed for advanced synthetic chemistry. This compound serves as a critical pharmaceutical intermediate and versatile building block for constructing complex heterocyclic molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to its bioactive pyrazine core.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the research and development of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Bromo-5-(Tetrahydro-Furan-3-Yloxy)Pyrazine
CAS No.	1086382-90-2
Molecular Formula	C8H9BrN2O2
Molecular Weight	245.07 g/mol
Synonyms	2-Bromo-5-[(oxolan-3-yl)oxy]pyrazine; 2-Bromo-5-(tetrahydro-3-furanyloxy)pyrazine; Pyrazine, 2-bromo-5-(tetrahydro-3-furanyloxy)-; 3-((5-Bromopyrazin-2-yl)oxy)tetrahydrofuran; 2-Bromo-5-(3-tetrahydrofuranyloxy)pyrazine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Tetrahydro-Furan-3-Yloxy)Pyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high standards, including cGMP (current Good Manufacturing Practice) for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed under an inert atmosphere if specified. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.