Description

2-Bromo-5-Cyclopropylpyrazine is a high-purity, functionalized pyrazine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the introduction of both bromine and cyclopropyl substituents into complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the bioactivity of the pyrazine core.
• Material Science Research: Serves as a precursor for designing functional organic materials, such as ligands for catalysts or components in organic electronics.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	2-Bromo-5-Cyclopropylpyrazine
CAS No.	1086382-78-6
Molecular Formula	C7H7BrN2
Molecular Weight	199.05 g/mol
Synonyms	5-Cyclopropyl-2-bromopyrazine; 2-Bromo-5-cyclopropylpyrazine; Bromocyclopropylpyrazine; Pyrazine, 2-bromo-5-cyclopropyl-; 1086382-78-6; 2-Bromo-5-(cyclopropyl)pyrazine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Cyclopropylpyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.