Description

5-Bromo-3-Methyl-1H-Pyrazolo[3,4-B]Pyrazine is a high-value brominated heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents, particularly in kinase inhibitor research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries. Its unique fused pyrazolo-pyrazine core offers versatile sites for further functionalization, enabling the creation of complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of targeted small-molecule drugs, especially protein kinase inhibitors for oncology and inflammatory diseases.
• Agrochemical Research: Used in the discovery and development of new active ingredients for crop protection products.
• Chemical Biology Probe Development: Serves as a scaffold for creating tool compounds to study biological pathways and enzyme functions.
• Material Science: Potential building block for organic electronic materials and advanced polymers due to its electron-deficient heterocyclic structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up for client projects.
• Academic Research: Utilized in university and institutional labs for methodological development and exploration of new chemical space.

Basic Information

Product Name	5-Bromo-3-Methyl-1H-Pyrazolo[3,4-B]Pyrazine
CAS No.	1086064-35-8
Molecular Formula	C7H5BrN4
Molecular Weight	225.05 g/mol
Synonyms	5-Bromo-3-methyl-1H-pyrazolo[3,4-b]pyrazine; 3-Methyl-5-bromo-1H-pyrazolo[3,4-b]pyrazine; 1H-Pyrazolo[3,4-b]pyrazine, 5-bromo-3-methyl-; 1086064-35-8; 5-Bromo-3-methylpyrazolo[3,4-b]pyrazine; 5-Bromo-3-methyl-1H-pyrazolo[3,4-b]pyrazin; 5-Bromo-3-methyl-1H-pyrazolo[3,4-b]pyrazine (CAS 1086064-35-8)
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Methyl-1H-Pyrazolo[3,4-B]Pyrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your regulatory needs in advanced research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.