Description

5-Pyrazin-2-Yl-1,3-Oxazole-4-Carboxylic Acid is a high-purity, heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its unique fused oxazole-pyrazine structure makes it a valuable precursor for developing novel pharmacologically active compounds. This intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other heterocyclic-based therapeutics.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the synthesis of organic semiconductors, conductive polymers, and other advanced functional materials due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized as a building block for synthesizing molecular probes and tags to study biological processes and protein interactions.

Basic Information

Product Name	5-Pyrazin-2-Yl-1,3-Oxazole-4-Carboxylic Acid
CAS No.	1083401-49-3
Molecular Formula	C8H5N3O3
Molecular Weight	191.15 g/mol
Synonyms	5-(Pyrazin-2-yl)-1,3-oxazole-4-carboxylic acid; 2-(4-Carboxy-1,3-oxazol-5-yl)pyrazine; 1,3-Oxazole-4-carboxylic acid, 5-(2-pyrazinyl)-; 5-(2-Pyrazinyl)-1,3-oxazole-4-carboxylic acid; 1083401-49-3; 5-Pyrazin-2-yloxazole-4-carboxylic acid; Oxazole-4-carboxylic acid, 5-pyrazin-2-yl-
EINECS	Contact for details

Quality Control

Every batch of 5-Pyrazin-2-Yl-1,3-Oxazole-4-Carboxylic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications, with purity typically exceeding 97% (HPLC). A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profile is provided with each shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is compatible with strong acids and organic solvents but should be kept separate from strong bases and oxidizing agents. Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.