Description

Ethanone, 2-Amino-1-[4-(Methylsulfonyl)-1-Piperazinyl]- is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperazine and methylsulfonyl functional groups. This compound is of significant commercial importance for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, especially for central nervous system (CNS) and anti-inflammatory drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for CNS-targeted therapies.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• API Synthesis: Serves as a precursor in the multi-step synthesis of complex active pharmaceutical ingredients.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in pharmaceutical labs.
• Biochemical Research: Utilized in the study of enzyme inhibition and receptor binding assays due to its specific pharmacophore.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing specialized compounds for client projects.

Basic Information

Product Name	Ethanone, 2-Amino-1-[4-(Methylsulfonyl)-1-Piperazinyl]-
CAS No.	1082425-86-2
Molecular Formula	C7H15N3O3S
Molecular Weight	221.28 g/mol
Synonyms	2-Amino-1-[4-(methylsulfonyl)piperazin-1-yl]ethanone; 1-(4-Methanesulfonylpiperazin-1-yl)-2-aminoethanone; 2-Amino-1-(4-methanesulfonylpiperazin-1-yl)ethan-1-one; 2-Amino-1-(4-methylsulfonyl-1-piperazinyl)ethanone; 1082425-86-2; AKOS025247315; A-1-[4-(Methylsulfonyl)-1-piperazinyl]-2-aminoethanone
EINECS	Contact for details

Quality Control

Our Ethanone, 2-Amino-1-[4-(Methylsulfonyl)-1-Piperazinyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, providing full traceability and compliance support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.