Description

2-Methyl-1-{4-[(1-Methyl-1H-Indol-2-Yl)Carbonyl]Piperazin-1-Yl}Propan-1-One is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules targeting specific receptors. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of innovative therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Biochemical Tool Compound: Serves as a reference standard or probe in pharmacological assays to study specific biological pathways.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex molecules with indole and piperazine motifs.
• Contract Research & Development (CRO): Supplied to CROs and academic institutions for proprietary research projects and hit-to-lead optimization.

Basic Information

Product Name	2-Methyl-1-{4-[(1-Methyl-1H-Indol-2-Yl)Carbonyl]Piperazin-1-Yl}Propan-1-One
CAS No.	1081133-21-2
Molecular Formula	C18H23N3O2
Molecular Weight	313.40 g/mol
Synonyms	1-(1-Methyl-1H-indole-2-carbonyl)-4-isobutyrylpiperazine; 4-(2-Methylpropanoyl)-1-[(1-methylindol-2-yl)carbonyl]piperazine; 2-Methyl-1-[4-[(1-methyl-1H-indol-2-yl)carbonyl]-1-piperazinyl]-1-propanone; UNII-9V6T2B5Q4M; 9V6T2B5Q4M; 1-(1-Methylindole-2-carbonyl)-4-isobutyrylpiperazine; Isobutyric acid (1-methyl-1H-indole-2-carbonyl)-piperazin-1-yl ester
EINECS	Contact for details

Quality Control

Our production of 2-Methyl-1-{4-[(1-Methyl-1H-Indol-2-Yl)Carbonyl]Piperazin-1-Yl}Propan-1-One adheres to stringent quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.