Description

6-Fluoro-3-Hydroxypyrazine-2-Carboxylic Acid is a high-value fluorinated pyrazine derivative, serving as a critical building block in modern synthetic chemistry. Its molecular structure, featuring both a carboxylic acid and a hydroxyl group on the heterocyclic ring, makes it an essential intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, where the fluorine atom enhances bioavailability and environmental stability.
• Ligand & Chelator Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design of fluorinated probes and tags for studying biological processes and enzyme mechanisms.
• Material Science: A potential monomer or modifier for creating specialty polymers with unique electronic or surface properties.

Basic Information

Product Name	6-Fluoro-3-Hydroxypyrazine-2-Carboxylic Acid
CAS No.	1079990-21-8
Molecular Formula	C5H3FN2O3
Molecular Weight	158.09 g/mol
Synonyms	6-Fluoro-3-hydroxypyrazine-2-carboxylic acid; 2-Carboxy-6-fluoro-3-hydroxypyrazine; 6-Fluoro-3-hydroxy-2-pyrazinecarboxylic acid; 1079990-21-8; 6-Fluoro-3-hydroxypyrazinecarboxylic acid; 3-Hydroxy-6-fluoropyrazine-2-carboxylic acid; 6-Fluoro-3-oxo-3,4-dihydropyrazine-2-carboxylic acid (tautomeric form)
EINECS	Contact for details

Quality Control

Our production of 6-Fluoro-3-Hydroxypyrazine-2-Carboxylic Acid adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques like HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality system is designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.