Description

1-Benzyl 4-[6-(5-Chloropyridin-2-Yl)-7-Oxo-6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyrazin-5-Yl]Piperazine-1,4-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel, targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical development companies engaged in the discovery of kinase inhibitors and other small molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for oncology and anti-inflammatory targets.
• Kinase Inhibitor Development: Serves as a core scaffold for research into novel protein kinase inhibitors due to its pyrrolopyrazine pharmacophore.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to develop new drug candidates.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for scale-up and cGMP production of clinical trial materials.
• Biochemical Research: May be utilized as a tool compound or reference standard in biochemical assays to study specific biological pathways.

Basic Information

Product Name	1-Benzyl 4-[6-(5-Chloropyridin-2-Yl)-7-Oxo-6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyrazin-5-Yl]Piperazine-1,4-Dicarboxylate
CAS No.	1076198-91-8
Molecular Formula	C24H21ClN6O5
Molecular Weight	508.91 g/mol
Synonyms	1-Benzyl 4-(6-(5-chloropyridin-2-yl)-7-oxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyrazin-5-yl)piperazine-1,4-dicarboxylate; 1,4-Piperazinedicarboxylic acid, 1-(phenylmethyl) 4-[6-(5-chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl] ester; UNII-6S1C2V7Q3F; 6S1C2V7Q3F; BCPPD; 1-Benzyl 4-(6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl)piperazine-1,4-dicarboxylate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for critical R&D and scale-up work. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and LC-MS. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and impurity profiles. We support development under quality agreements and can align with cGMP standards for projects requiring regulatory filing.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.