Description

Methyl 2-Amino-3-Bromopyrazine-5-Carboxylate CAS NO 1076198-49-6 is a high-purity, functionalized pyrazine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogenated and esterified structure, which enables precise molecular modifications in complex chemical pathways. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions due to the reactive bromine atom.
• Academic & Contract Research: Essential for methodological studies and library synthesis in academic laboratories and contract research organizations (CROs).
• Dye & Pigment Intermediate: Acts as a building block for synthesizing nitrogen-containing heterocyclic dyes and colorants.

Basic Information

Item	Detail
Product Name	Methyl 2-Amino-3-Bromopyrazine-5-Carboxylate
CAS No.	1076198-49-6
Molecular Formula	C7H8BrN3O2
Molecular Weight	246.06 g/mol
Synonyms	2-Amino-3-bromo-5-(methoxycarbonyl)pyrazine; Methyl 2-amino-3-bromopyrazine-5-carboxylate; 3-Bromo-2-aminopyrazine-5-carboxylic acid methyl ester; 5-Carbomethoxy-2-amino-3-bromopyrazine; 2-Amino-3-bromopyrazine-5-carboxylic acid methyl ester; Methyl 3-bromo-2-aminopyrazine-5-carboxylate; 1076198-49-6
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-3-Bromopyrazine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.