Description

Pyrrolo[1,2-A]Pyrazine, Octahydro-3-Methyl-, (3S,8Ar)- is a high-purity, stereochemically defined heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its rigid, fused bicyclic structure, which serves as a key chiral scaffold for constructing complex molecules with precise three-dimensional orientation. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, process development, and the synthesis of novel active ingredients. The CAS number for this specific stereoisomer is 1072102-45-4.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used as a building block for creating novel, stereoselective pesticides and herbicides with enhanced efficacy and environmental profiles.
• Asymmetric Catalysis Ligand Precursor: Its defined stereochemistry makes it a valuable starting material for synthesizing novel chiral ligands and organocatalysts.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new chemical space and optimize the biological activity of lead compounds.
• Process Chemistry & Scale-Up: Provides a consistent, high-quality starting point for developing robust and scalable synthetic routes to target molecules.
• Academic Research: Used in universities and research institutes for methodological studies in heterocyclic and stereoselective synthesis.

Basic Information

Product Name	Pyrrolo[1,2-A]Pyrazine, Octahydro-3-Methyl-, (3S,8Ar)-
CAS No.	1072102-45-4
Molecular Formula	C8H14N2
Molecular Weight	138.21 g/mol
Synonyms	(3S,8aR)-Octahydro-3-methylpyrrolo[1,2-a]pyrazine; (3S,8aR)-3-Methyloctahydropyrrolo[1,2-a]pyrazine; (3S,8aR)-3-Methyl-1,2,3,5,6,7,8,8a-octahydropyrrolo[1,2-a]pyrazine; (3S,8aR)-3-Methylhexahydro-1H-pyrrolo[1,2-a]pyrazine; Chiral Pyrrolopyrazine Derivative; 3-Methyloctahydropyrrolo[1,2-a]pyrazine (S,R-isomer)
EINECS	Contact for details

Quality Control

Every batch of our Pyrrolo[1,2-A]Pyrazine, Octahydro-3-Methyl-, (3S,8Ar)- is produced under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), enantiomeric excess (Chiral HPLC or GC), and impurity profiles. Our commitment to consistent quality and documentation supports your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.