Description

(3S,8As)-3-Isobutyloctahydropyrrolo[1,2-A]Pyrazine CAS NO 1072102-31-8 is a high-purity, stereochemically defined heterocyclic compound belonging to the pyrrolopyrazine class. This advanced pharmaceutical intermediate is valued for its unique structural framework, which serves as a critical building block in modern medicinal chemistry. It is primarily sought by research and development teams in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and investigational compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing complex molecular libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable synthesis of target molecules during clinical development phases.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or precursor in stereoselective synthesis to introduce specific three-dimensional configurations into target molecules.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs engaged in custom synthesis projects requiring high-fidelity chiral intermediates.

Basic Information

Product Name	(3S,8As)-3-Isobutyloctahydropyrrolo[1,2-A]Pyrazine
CAS No.	1072102-31-8
Molecular Formula	C12H22N2
Molecular Weight	194.32 g/mol
Synonyms	(3S,8aS)-3-(2-Methylpropyl)octahydro-1H-pyrrolo[1,2-a]pyrazine; (3S,8aS)-3-Isobutylhexahydro-1H-pyrrolo[1,2-a]pyrazine; Pyrrolo[1,2-a]pyrazine, octahydro-3-(2-methylpropyl)-, (3S,8aS)-; (3S,8aS)-3-Isobutyloctahydro-1H-pyrrolo[1,2-a]pyrazine; (3S,8aS)-3-(2-Methylpropyl)octahydro-1H-pyrrolo[1,2-a]pyrazine; Stereoisomer of 3-Isobutyloctahydropyrrolo[1,2-a]pyrazine
EINECS	Contact for details

Quality Control

Our (3S,8As)-3-Isobutyloctahydropyrrolo[1,2-A]Pyrazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.