Description

tert-Butyl 4-(4-Chlorophenyl)Piperazine-1-Carboxylate is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents. Pharmaceutical R&D laboratories and fine chemical manufacturers need it to construct complex molecular architectures with precision and reliability.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in neurological and psychiatric research.
• Active Pharmaceutical Ingredient (API) Development: Used in constructing the core pharmacophore of potential therapeutic molecules.
• Chemical Research & Development: Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical production.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	tert-Butyl 4-(4-Chlorophenyl)Piperazine-1-Carboxylate
CAS No.	1070716-32-3
Molecular Formula	C15H21ClN2O2
Molecular Weight	296.79 g/mol
Synonyms	1-Boc-4-(4-Chlorophenyl)piperazine; 4-(4-Chlorophenyl)-1-piperazinecarboxylic acid tert-butyl ester; tert-Butyl 4-(4-chlorophenyl)-1-piperazinecarboxylate; 1-(tert-Butoxycarbonyl)-4-(4-chlorophenyl)piperazine; Boc-4-(4-Chlorophenyl)piperazine; 4-(p-Chlorophenyl)-1-Boc-piperazine; 4-(4-Chlorophenyl)piperazine-1-carboxylic acid tert-butyl ester; N-Boc-4-(4-chlorophenyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Chlorophenyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. While not a pharmacopeial material, production adheres to cGMP principles where applicable to support its use in pharmaceutical development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.