Description

tert-Butyl 3-Fluoropiperidine-1-Carboxylate is a high-purity, protected piperidine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing the 3-fluoropiperidine pharmacophore, a key structural motif in medicinal chemistry. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of central nervous system (CNS) active drugs, kinase inhibitors, and other bioactive molecules.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides that incorporate fluorinated heterocycles for enhanced efficacy.
• Chemical Biology: Serves as a versatile scaffold for constructing molecular probes and libraries to study biological pathways.
• Process Chemistry: Employed in route scouting and scale-up for the commercial production of fluorinated active pharmaceutical ingredients (APIs).
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs to produce bespoke compounds for client projects.

Basic Information

Product Name	tert-Butyl 3-Fluoropiperidine-1-Carboxylate
CAS No.	1068560-26-8
Molecular Formula	C10H18FNO2
Molecular Weight	203.26 g/mol
Synonyms	1-Boc-3-fluoropiperidine; 3-Fluoro-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 3-fluoropiperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-fluoropiperidine; 3-Fluoropiperidine-1-carboxylic acid tert-butyl ester; Boc-3-fluoropiperidine; N-Boc-3-fluoropiperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Fluoropiperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.