Description

(R)-1-Ethyl-5-Methylpiperazin-2-One CAS NO 1068149-98-3 is a chiral piperazinone derivative, a high-value building block in advanced organic synthesis. Its enantiopure structure is critical for imparting specific stereochemistry and biological activity in complex molecules. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides where specific stereochemistry affects efficacy and environmental profile.
• Ligand & Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Advanced Material Synthesis: A building block for creating specialty polymers and functional materials with tailored properties.

Basic Information

Product Name	(R)-1-Ethyl-5-Methylpiperazin-2-One
CAS No.	1068149-98-3
Molecular Formula	C7H14N2O
Molecular Weight	142.20 g/mol
Synonyms	(R)-1-Ethyl-5-methylpiperazin-2-one; (R)-1-Ethyl-5-methyl-2-piperazinone; (R)-5-Methyl-1-ethylpiperazin-2-one; (2R)-1-Ethyl-5-methylpiperazin-2-one; (R)-1-Ethyl-5-methyl-2,3,4,5-tetrahydropyrazin-2-one; (R)-EMPO; (R)-1-Ethyl-5-methyl-2-oxopiperazine
EINECS	Contact for details

Quality Control

Our (R)-1-Ethyl-5-Methylpiperazin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced research applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when appropriate to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.