Description

(R)-1-Ethyl-5-Methylpiperazin-2-One is a chiral piperazinone derivative, a high-value building block in advanced organic synthesis. Its enantiopure nature is critical for developing pharmaceuticals with specific stereochemical requirements, ensuring high biological activity and purity. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, especially for neurological and psychiatric disorders.
• Asymmetric Synthesis: Used as a precursor or catalyst ligand in stereoselective reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Potential application in the synthesis of enantiomerically pure agrochemicals for enhanced efficacy and environmental safety.
• Academic & Industrial R&D: Utilized in chemical research for studying reaction mechanisms and developing new synthetic methodologies involving piperazinone chemistry.

Basic Information

Product Name	(R)-1-Ethyl-5-Methylpiperazin-2-One
CAS No.	1068149-96-1
Molecular Formula	C7H14N2O
Molecular Weight	142.20 g/mol
Synonyms	(R)-1-Ethyl-5-methyl-2-piperazinone; (R)-1-Ethyl-5-methylpiperazin-2-one; (R)-5-Methyl-1-ethylpiperazin-2-one; (R)-1-Ethyl-5-methyl-2,3,4,5-tetrahydropyrazin-2-one; (2R)-1-Ethyl-5-methylpiperazin-2-one; (R)-1-Ethyl-5-methyl-2-oxopiperazine; (R)-EMPO; (R)-1-Ethyl-5-methylpiperazinone
EINECS	Contact for details

Quality Control

Our (R)-1-Ethyl-5-Methylpiperazin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.