Description

(S)-3-(4-n-Methyl-Piperazin-1-Yl)Pyrrolidine-3Hcl is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals, offering precise stereochemical control. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology drug candidates.
• Ligand Synthesis: Used in the preparation of sophisticated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Serves as a building block for developing new-generation pesticides and herbicides with enhanced efficacy.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme inhibition.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects.

Basic Information

Product Name	(S)-3-(4-n-Methyl-Piperazin-1-Yl)Pyrrolidine-3Hcl
CAS No.	1067716-49-7
Molecular Formula	C9H20N3Cl3 (Note: Represents the trihydrochloride salt form)
Molecular Weight	Contact for details
Synonyms	(S)-3-(4-Methylpiperazin-1-yl)pyrrolidine trihydrochloride; (S)-3-(4-Methyl-1-piperazinyl)-1-pyrrolidine trihydrochloride; (3S)-3-(4-Methylpiperazin-1-yl)pyrrolidine hydrochloride (1:3); 1067716-49-7; (S)-3-(4-Methylpiperazinyl)pyrrolidine 3HCl; Pyrrolidine, 3-(4-methyl-1-piperazinyl)-, (3S)-, trihydrochloride
EINECS	Contact for details

Quality Control

Our (S)-3-(4-n-Methyl-Piperazin-1-Yl)Pyrrolidine-3Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.