Description

1-Boc-4-(2,4-Difluorobenzyl)Piperazine is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs), enabling precise molecular modifications. Pharmaceutical researchers and fine chemical manufacturers need it for constructing complex molecules, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Key synthon in the research and development of new drug candidates, especially for CNS-targeted therapies.
• API Synthesis: Used in the multi-step synthesis of complex active pharmaceutical ingredients requiring a protected piperazine moiety.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds.
• Chemical Biology: Useful as a molecular scaffold or linker in probe and tool compound development.

Basic Information

Product Name	1-Boc-4-(2,4-Difluorobenzyl)Piperazine
CAS No.	1065586-31-3
Molecular Formula	C17H24F2N2O2
Molecular Weight	326.38 g/mol
Synonyms	1-Boc-4-(2,4-Difluorobenzyl)piperazine; tert-Butyl 4-(2,4-difluorobenzyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(2,4-difluorobenzyl)piperazine; N-Boc-4-(2,4-Difluorobenzyl)piperazine; Piperazine, 1-(1,1-dimethylethoxy)carbonyl-4-[(2,4-difluorophenyl)methyl]-; 4-(2,4-Difluorobenzyl)piperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(2,4-Difluorobenzyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full batch traceability are provided to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.