Description

2-Chloro-n-(1-Pyrazin-2-Yl-Piperidin-4-Yl)-Acetamide is a high-purity (98+%) organic building block with the molecular formula C11H15ClN4O and a molecular weight of 254.72. This compound is a critical intermediate in modern pharmaceutical research and development, valued for its unique piperazine-pyrazine core structure. It is primarily utilized by medicinal chemists and process development scientists in the synthesis of novel active pharmaceutical ingredients (APIs) and for high-throughput screening libraries.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: An essential starting material for CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for clients.
• Library Synthesis for HTS: Incorporated into diverse compound libraries used in high-throughput screening (HTS) to identify new biological hits.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.

Basic Information

Product Name	2-Chloro-n-(1-Pyrazin-2-Yl-Piperidin-4-Yl)-Acetamide, 98+%
CAS No.	1065484-52-7
Molecular Formula	C11H15ClN4O
Molecular Weight	254.72 g/mol
Synonyms	2-Chloro-N-[1-(pyrazin-2-yl)piperidin-4-yl]acetamide; 2-Chloro-N-(1-(pyrazin-2-yl)piperidin-4-yl)acetamide; 2-Chloroacetamide, N-[1-(2-pyrazinyl)-4-piperidinyl]-; 1065484-52-7; N-(1-(Pyrazin-2-yl)piperidin-4-yl)-2-chloroacetamide; 2-Chloro-N-(1-pyrazin-2-ylpiperidin-4-yl)acetamide; 2-Chloro-N-[1-(2-pyrazinyl)-4-piperidinyl]acetamide
EINECS	Contact for details

Quality Control

Our 2-Chloro-n-(1-Pyrazin-2-Yl-Piperidin-4-Yl)-Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the specified 98+% purity standard and is free from critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.