Description

(5-Chloropyrazin-2-Yl)Methanamine is a high-purity, functionalized pyrazine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional nature, featuring both a reactive chloropyrazine core and a primary amine handle, enabling diverse derivatization for creating complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to construct novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the pyrazine scaffold's bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the synthesis of organic semiconductors, conductive polymers, and other functional organic materials due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized as a starting point for synthesizing molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A fundamental building block supplied to custom synthesis organizations (CSOs) and CROs for client-directed research and scale-up projects.

Basic Information

Product Name	(5-Chloropyrazin-2-Yl)Methanamine
CAS No.	1060814-53-0
Molecular Formula	C5H6ClN3
Molecular Weight	143.57 g/mol
Synonyms	1-(5-Chloropyrazin-2-yl)methanamine; (5-Chloro-2-pyrazinyl)methanamine; 2-Aminomethyl-5-chloropyrazine; 5-Chloro-2-pyrazinemethanamine; 5-Chloropyrazine-2-methylamine; 5-Chloro-2-(aminomethyl)pyrazine; (5-Chloro-pyrazin-2-yl)-methylamine; 2-(Aminomethyl)-5-chloropyrazine
EINECS	Contact for details

Quality Control

Our (5-Chloropyrazin-2-Yl)Methanamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where required, ensuring reliability for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.