Description

1-(5-(Trifluoromethyl)Pyrazin-2-Yl)Ethan-1-One is a high-value trifluoromethylated pyrazine derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a pyrazine ring and a trifluoromethyl group, makes it an essential intermediate for the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of drug candidates, particularly in areas like kinase inhibitors, antiviral agents, and central nervous system (CNS) therapeutics.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and bioactivity.
• Material Science Precursor: Serves as a building block for creating functionalized heterocyclic compounds used in organic electronics and advanced polymers.
• Chemical Biology Probe Development: Employed in medicinal chemistry to create molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized fluorinated heterocycles.

Basic Information

Product Name	1-(5-(Trifluoromethyl)Pyrazin-2-Yl)Ethan-1-One
CAS No.	1060812-68-1
Molecular Formula	C7H5F3N2O
Molecular Weight	190.12 g/mol
Synonyms	1-[5-(Trifluoromethyl)pyrazin-2-yl]ethanone; 2-Acetyl-5-(trifluoromethyl)pyrazine; Ethanone, 1-[5-(trifluoromethyl)-2-pyrazinyl]-; 5-(Trifluoromethyl)pyrazin-2-yl methyl ketone; 2-Acetyl-5-trifluoromethylpyrazine; 1-(5-Trifluoromethyl-pyrazin-2-yl)-ethanone; 5-(Trifluoromethyl)-2-acetylpyrazine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Every batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) are provided with each shipment, detailing batch-specific results. We adhere to a cGMP-compliant quality management system where applicable, ensuring traceability and consistency for critical pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.