Description

tert-Butyl 2-Isobutylpiperazine-1-Carboxylate is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile and reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). Pharmaceutical researchers and fine chemical manufacturers need this intermediate for its role in creating potential therapeutic agents, including central nervous system (CNS) drugs and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly for neurological and psychiatric applications.
• Organic Synthesis Building Block: Used in multi-step synthetic routes to introduce the protected 2-isobutylpiperazine moiety into more complex molecular architectures.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material or intermediate for custom synthesis projects in fine chemical and CDMO (Contract Development and Manufacturing Organization) facilities.
• Chemical Reference Standard: Can be utilized as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	tert-Butyl 2-Isobutylpiperazine-1-Carboxylate
CAS No.	1060807-66-0
Molecular Formula	C13H26N2O2
Molecular Weight	242.36 g/mol
Synonyms	1-Boc-2-isobutylpiperazine; 2-Isobutyl-1-(tert-butoxycarbonyl)piperazine; tert-Butyl 2-(2-methylpropyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-2-isobutylpiperazine; Boc-2-isobutylpiperazine; 2-(Isobutyl)-1-Boc-piperazine; Piperazine, 2-(2-methylpropyl)-, 1-(1,1-dimethylethyl) ester; 1060807-66-0
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Isobutylpiperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We adhere to cGMP (current Good Manufacturing Practice) guidelines where applicable to support our clients in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.