Description

Methyl-Peg20-Alcohol CAS NO 1059605-06-9 is a high-purity, monodisperse polyethylene glycol (PEG) derivative, specifically a methyl ether of a 20-unit PEG chain terminated with a hydroxyl group. This precise chemical structure makes it an invaluable non-ionic surfactant and hydrophilic spacer for advanced formulation chemistry. It is essential for industries requiring controlled hydrophilicity, solubility enhancement, and biocompatible surface modification.

Application

• Pharmaceutical Excipient & Drug Conjugation: Used as a solubilizing agent, co-solvent, and as a linker in PEGylation to improve the pharmacokinetic profiles of therapeutic proteins and peptides.
• Bioconjugation & Diagnostic Reagents: Serves as a hydrophilic spacer arm for attaching labels, dyes, or targeting molecules to antibodies, proteins, and nanoparticles in assay development.
• Polymer & Material Science: Acts as a macromonomer or initiator for synthesizing block copolymers, hydrogels, and functionalized surfaces with tailored properties.
• Personal Care & Cosmetics: Employed as a mild surfactant, humectant, and viscosity modifier in high-performance skincare and haircare formulations.
• Lubricants & Functional Fluids: Functions as a base fluid or additive in synthetic lubricants due to its thermal stability and low toxicity.
• Chemical Synthesis Intermediate: Provides a reactive hydroxyl terminus for further functionalization to create custom PEG-based derivatives.

Basic Information

Item	Detail
Product Name	Methyl-Peg20-Alcohol
CAS No.	1059605-06-9
Molecular Formula	C41H84O21
Molecular Weight	~ 948.1 g/mol
Synonyms	Methoxy-PEG20-OH; mPEG20-OH; Poly(ethylene glycol) methyl ether (n~20); 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol; PEG Methyl Ether (MW ~950); α-Methyl-ω-hydroxy-poly(oxy-1,2-ethanediyl); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our Methyl-Peg20-Alcohol is manufactured under a cGMP-compliant quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and assay, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets stringent specifications for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) documenting identity, purity, and relevant impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at 15-25°C. This product is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere (nitrogen or argon), please contact our technical team.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Average Molecular Weight (GPC)	950 ± 50
Polydispersity Index (PDI)	≤ 1.05
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.