Description

Methyl 2-(1,3-Dioxo-1,2,3,4-Tetrahydropyrrolo[1,2-A]Pyrazin-4-Yl)Acetate is a high-purity, heterocyclic organic compound that serves as a critical synthetic intermediate in advanced pharmaceutical research and development. Its unique fused pyrrolopyrazine-dione structure makes it a valuable building block for constructing complex molecules with potential biological activity. This compound is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in the scale-up and route scouting for the commercial manufacturing of complex target molecules.
• Bioconjugation & Probe Synthesis: Serves as a starting material for creating chemical probes and bioconjugates used in biochemical assays and diagnostic research.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for exploratory synthetic chemistry and methodology development.

Basic Information

Product Name	Methyl 2-(1,3-Dioxo-1,2,3,4-Tetrahydropyrrolo[1,2-A]Pyrazin-4-Yl)Acetate
CAS No.	1059195-96-8
Molecular Formula	C11H10N2O4
Molecular Weight	234.21 g/mol
Synonyms	Methyl (1,3-dioxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl)acetate; 4-(Methoxycarbonylmethyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-1,3-dione; 1,2,3,4-Tetrahydropyrrolo[1,2-a]pyrazine-1,3-dione, 4-(carboxymethyl)-, methyl ester; Methyl 2-(1,3-dioxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl)ethanoate; Pyrrolo[1,2-a]pyrazine-1,3(2H,4H)-dione, 4-(carboxymethyl)-, methyl ester; CAS 1059195-96-8
EINECS	Contact for details

Quality Control

Our Methyl 2-(1,3-Dioxo-1,2,3,4-Tetrahydropyrrolo[1,2-A]Pyrazin-4-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.