Description

Alpha,ω-Bis-Hydroxy 28(Ethylene Glycol) is a precisely defined, high-purity polyethylene glycol (PEG) derivative with terminal hydroxyl groups. This compound is a critical building block for synthesizing advanced polymers and functional materials, offering controlled molecular weight and predictable reactivity. It is essential for R&D and production in the pharmaceutical, specialty chemical, and advanced materials sectors where precise chain length and end-group functionality are paramount.

Application

• Pharmaceutical Intermediates: Serves as a key starting material or spacer for the synthesis of prodrugs, bioconjugates, and drug delivery systems like PEGylated proteins and nanoparticles.
• Polymer Synthesis: Acts as a macroinitiator or monomer for creating block copolymers, polyurethanes, polyesters, and other specialty polymers with tailored properties.
• Surface Modification: Used to create hydrophilic, protein-resistant, or biocompatible coatings on medical devices, sensors, and diagnostic platforms.
• Crosslinking Agent: Functions as a flexible crosslinker in hydrogel formulations for biomedical and cosmetic applications.
• Lubricant & Plasticizer Precursor: A precursor for high-performance synthetic lubricants and specialty plasticizers requiring specific chain lengths.
• Material Science Research: Employed in academic and industrial R&D for developing novel functional materials, dendrimers, and supramolecular structures.

Basic Information

Product Name	Alpha,ω-Bis-Hydroxy 28(Ethylene Glycol)
CAS No.	1053658-70-0
Molecular Formula	C56H114O29
Molecular Weight	~1251.5 g/mol
Synonyms	28-Mer Polyethylene Glycol; PEG 1000 Diol (approx.); α,ω-Dihydroxypoly(oxy-1,2-ethanediyl) (n≈28); Poly(ethylene glycol) 1000; HO-PEG28-OH; 1,1'-[1,2-ethanediylbis(oxy)]bis-2,2'-[oxybis(2,1-ethanediyloxy)]-...ethanol; Polyoxyethylene (28) glycol; Bishydroxy PEG 28
EINECS	Contact for details

Quality Control

Our Alpha,ω-Bis-Hydroxy 28(Ethylene Glycol) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, precise molecular weight distribution, and consistent performance. Certificates of Analysis (COA) detailing key parameters such as assay, hydroxyl value, polydispersity index, and residual solvents are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white waxy solid
Identification (IR)	Conforms
Assay (HPLC)	≥ 95.0%
Average Molecular Weight (GPC)	1150 - 1350 g/mol
Polydispersity Index (PDI)	≤ 1.10
Hydroxyl Value (Titration)	85 - 100 mg KOH/g
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.