Description

tert-Butyl 2-Cyanopiperazine-1-Carboxylate is a high-value, multi-functional piperazine derivative serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both a protected amine and a nitrile group, makes it an indispensable intermediate for constructing complex nitrogen-containing heterocycles. This compound is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: Key synthon in the research and production of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Ligand and Catalyst Synthesis: Used to prepare sophisticated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics & Constrained Peptides: The piperazine core and nitrile functionality are instrumental in designing conformationally restricted peptide analogs for medicinal chemistry.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides, fungicides, and insecticides.
• Dye and Pigment Chemistry: Employed in the synthesis of specialized heterocyclic dyes and colorants.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	tert-Butyl 2-Cyanopiperazine-1-Carboxylate
CAS No.	1053656-76-0
Molecular Formula	C10H17N3O2
Molecular Weight	211.26 g/mol
Synonyms	1-Boc-2-cyanopiperazine; tert-Butyl 2-cyano-1-piperazinecarboxylate; 2-Cyano-1-piperazinecarboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-2-cyanopiperazine; Boc-2-cyanopiperazine; 2-Cyanopiperazine-1-carboxylic acid tert-butyl ester; Piperazine-1-carboxylic acid, 2-cyano-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Cyanopiperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.