Description

4-[1-(2-Chlorobenzyl)-2,5-Dimethyl-1H-Pyrrol-3-Yl]-1,3-Thiazol-2-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor or core structure in the development of new APIs requiring a pyrrole-thiazole pharmacophore.
• Biochemical Research: Potential tool compound for studying enzyme inhibition or receptor modulation in biochemical assays.
• Contract Research and Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	4-[1-(2-Chlorobenzyl)-2,5-Dimethyl-1H-Pyrrol-3-Yl]-1,3-Thiazol-2-Amine Hydrochloride
CAS No.	1052548-30-7
Molecular Formula	C16H17ClN3S • HCl
Molecular Weight	356.71 g/mol
Synonyms	2-Thiazolamine, 4-[1-[(2-chlorophenyl)methyl]-2,5-dimethyl-1H-pyrrol-3-yl]-, hydrochloride (1:1); 4-(1-(2-Chlorobenzyl)-2,5-dimethyl-1H-pyrrol-3-yl)thiazol-2-amine hydrochloride; 1052548-30-7; UNII-9F4Q2S2V1I; 9F4Q2S2V1I; AKOS025147064; 4-[1-(2-Chlorobenzyl)-2,5-dimethylpyrrol-3-yl]-1,3-thiazol-2-amine hydrochloride; 4-[1-[(2-Chlorophenyl)methyl]-2,5-dimethyl-1H-pyrrol-3-yl]-1,3-thiazol-2-amine hydrochloride
EINECS	Contact for details

Quality Control

Our production of 4-[1-(2-Chlorobenzyl)-2,5-Dimethyl-1H-Pyrrol-3-Yl]-1,3-Thiazol-2-Amine Hydrochloride adheres to stringent quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.