Description

tert-Butyl 4-{[5-(4-Methylphenyl)-1H-Pyrazol-3-Yl]Carbonyl}Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile piperazine-pyrazole scaffold for targeted drug discovery. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• API Development: Serves as a critical precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Biochemical Tool Compound: Potential use in biochemical assays and as a probe for studying specific biological targets.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and pharmaceutical science projects.

Basic Information

Item	Details
Product Name	tert-Butyl 4-{[5-(4-Methylphenyl)-1H-Pyrazol-3-Yl]Carbonyl}Piperazine-1-Carboxylate
CAS No.	1050286-32-2
Molecular Formula	C20H26N4O3
Molecular Weight	370.45 g/mol
Synonyms	1-Boc-4-[(5-(p-tolyl)-1H-pyrazol-3-yl)carbonyl]piperazine; tert-Butyl 4-({5-[4-(Methyl)phenyl]-1H-pyrazol-3-yl}carbonyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-{[5-(4-methylphenyl)-1H-pyrazol-3-yl]carbonyl}piperazine; BOC-Piperazine-Pyrazole Intermediate; 1050286-32-2; 4-({5-[4-(Methyl)phenyl]-1H-pyrazol-3-yl}carbonyl)-1-piperazinecarboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-{[5-(4-Methylphenyl)-1H-Pyrazol-3-Yl]Carbonyl}Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.