Description

Neopentyl-(2-Nitro-5-Piperazin-1-Yl-Phenyl)Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific piperazine and nitro-substituted aniline structure. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in synthesizing complex drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Chemical Biology Research: Used as a probe or precursor in the development of enzyme inhibitors and receptor modulators due to its piperazine pharmacophore.
• Agrochemical Development: Functions as an intermediate in the research of new crop protection agents and pesticides.
• Material Science Research: Investigated as a monomer or functional component in the development of specialty polymers and advanced materials.
• Academic & Industrial R&D: Employed in universities and corporate labs for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Neopentyl-(2-Nitro-5-Piperazin-1-Yl-Phenyl)Amine Hydrochloride
CAS No.	1050208-15-5
Molecular Formula	C15H23N5O2 · HCl
Molecular Weight	349.84 g/mol (Free base: 313.38 g/mol)
Synonyms	1-(4-((Neopentylamino)-2-nitrophenyl)piperazine hydrochloride; 2-Nitro-N-neopentyl-5-(piperazin-1-yl)aniline hydrochloride; 5-(Piperazin-1-yl)-N-(2,2-dimethylpropyl)-2-nitroaniline hydrochloride; N-(2,2-Dimethylpropyl)-5-(piperazin-1-yl)-2-nitrobenzenamine hydrochloride; Neopentyl-(2-nitro-5-piperazinylphenyl)amine HCl; CAS 1050208-15-5
EINECS	Contact for details

Quality Control

Our Neopentyl-(2-Nitro-5-Piperazin-1-Yl-Phenyl)Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.