Description

2-(1-Isobutyl-2-Piperazinyl)-1-Ethanoldihydrochloride is a high-purity, specialized piperazine derivative used as a critical intermediate in advanced pharmaceutical synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) targeting neurological and cardiovascular systems. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the production of novel therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those with CNS (Central Nervous System) activity.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemists exploring new structure-activity relationships (SAR).
• API (Active Pharmaceutical Ingredient) Synthesis: Used in the production pathway for specific, high-potency therapeutic agents.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industries.
• Reference Standard: Can be supplied as a certified reference material for analytical method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	2-(1-Isobutyl-2-Piperazinyl)-1-Ethanoldihydrochloride
CAS No.	1049750-12-0
Molecular Formula	C10H23N2O·2HCl
Molecular Weight	267.22 g/mol (free base: 187.31 g/mol)
Synonyms	1-(2-Hydroxyethyl)-4-isobutylpiperazine Dihydrochloride; 2-(4-Isobutylpiperazin-1-yl)ethanol Dihydrochloride; 4-Isobutyl-1-(2-hydroxyethyl)piperazine Dihydrochloride; 1-Isobutyl-4-(2-hydroxyethyl)piperazine Dihydrochloride; 2-(1-Isobutylpiperazin-2-yl)ethan-1-ol Dihydrochloride; N-Isobutyl-N'-(2-hydroxyethyl)piperazine Dihydrochloride; CAS 1049750-12-0
EINECS	Contact for details

Quality Control

Our 2-(1-Isobutyl-2-Piperazinyl)-1-Ethanoldihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, identity confirmation by FT-IR and NMR, and tests for residual solvents and related substances, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm
Related Substances (HPLC)	Total impurities < 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.