Description

Octahydro-Pyrido[1,2-A]Pyrazine-7-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex bicyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and other therapeutic agents. It is primarily required by R&D laboratories, custom synthesis providers, and pharmaceutical manufacturers engaged in innovative drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting neurological pathways.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing novel heterocyclic compounds and exploring new chemical spaces.
• Process Chemistry Development: Serves as a critical starting material or intermediate for scaling up API manufacturing processes under GMP conditions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of proprietary compounds for clients.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in API production.

Basic Information

Product Name	Octahydro-Pyrido[1,2-A]Pyrazine-7-Carboxylic Acid
CAS No.	1049677-81-7
Molecular Formula	C9H14N2O2
Molecular Weight	182.22 g/mol
Synonyms	7-Carboxyoctahydro-1H-pyrido[1,2-a]pyrazine; Octahydro-1H-pyrido[1,2-a]pyrazine-7-carboxylic acid; 1H-Pyrido[1,2-a]pyrazine-7-carboxylic acid, octahydro-; (7S)-Octahydro-1H-pyrido[1,2-a]pyrazine-7-carboxylic acid (for stereoisomers); Bicyclic proline derivative; Pyrido-pyrazine carboxylic acid intermediate
EINECS	Contact for details

Quality Control

Our Octahydro-Pyrido[1,2-A]Pyrazine-7-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.