Description

2-Bromo-5-(Methylthio)Pyrazine is a high-purity, functionalized pyrazine derivative serving as a critical building block in advanced organic synthesis. Its unique halogenated and thioether structure makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromine and sulfur functionalities into their target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a brominated pyrazine core for further functionalization or as a leaving group in cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the pyrazine ring contributes to biological activity and the bromine atom allows for structural diversification.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis, leveraging the sulfur and nitrogen donor atoms.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for organic light-emitting diodes (OLEDs) or conductive polymers, where heterocyclic units are fundamental.
• Flavor and Fragrance Chemistry: Acts as a potential intermediate for synthesizing complex aroma compounds, as alkylpyrazines are known for their nutty, roasted flavor notes.

Basic Information

Product Name	2-Bromo-5-(Methylthio)Pyrazine
CAS No.	1049026-49-4
Molecular Formula	C5H5BrN2S
Molecular Weight	205.08 g/mol
Synonyms	5-(Methylthio)-2-bromopyrazine; 2-Bromo-5-methylsulfanylpyrazine; 2-Bromo-5-(methylmercapto)pyrazine; Pyrazine, 2-bromo-5-(methylthio)-; 2-Bromo-5-methylthiopyrazine; 2-Bromanyl-5-methylsulfanylpyrazine
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-(Methylthio)Pyrazine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and custom specifications can be developed to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.