Description

tert-Butyl 4-(Isoquinolin-3-Yl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core linked to an isoquinoline moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for synthesizing novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Kinase Inhibitor Development: Serves as a core structure in the design and synthesis of novel kinase inhibitors for cancer therapy.
• CNS-Active Compound Synthesis: Employed in the creation of compounds intended to cross the blood-brain barrier for neurological applications.
• Chemical Biology Probes: Utilized to develop tool compounds for probing biological mechanisms and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke molecules under cGMP conditions.

Basic Information

Product Name	tert-Butyl 4-(Isoquinolin-3-Yl)Piperazine-1-Carboxylate
CAS No.	1042986-15-1
Molecular Formula	C18H23N3O2
Molecular Weight	313.40 g/mol
Synonyms	1-Boc-4-(isoquinolin-3-yl)piperazine; 3-(1-Boc-piperazin-4-yl)isoquinoline; tert-Butyl 4-(3-isoquinolyl)-1-piperazinecarboxylate; 1-Piperazinecarboxylic acid, 4-(3-isoquinolinyl)-, 1,1-dimethylethyl ester; 1042986-15-1; BOC-Piperazine-Isoquinoline; tert-Butyl 4-(isoquinolin-3-yl)piperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(Isoquinolin-3-Yl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development under ISO guided standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.