Description

2-Pyrazinecarbonitrile, 5-[4-(2-Bromo-5-Fluorophenoxy)-1-Piperidinyl]- is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters for its precise molecular architecture, which enables the construction of complex pharmacophores and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and intermediates. The CAS number for this compound is 1042428-54-5.

Application

This versatile intermediate is engineered for precision applications in research and development, particularly where structural complexity and specific substitution patterns are required.

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging its halogenated phenoxy and piperidinyl motifs.
• Chemical Biology Probes: Serves as a precursor for creating labeled compounds or probes used in biochemical assays and target identification.
• Material Science Precursor: Can be utilized in the synthesis of specialized ligands for catalysts or functional organic materials.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses producing bespoke intermediates for client R&D pipelines.

Basic Information

Product Name	2-Pyrazinecarbonitrile, 5-[4-(2-Bromo-5-Fluorophenoxy)-1-Piperidinyl]-
CAS No.	1042428-54-5
Molecular Formula	C16H14BrFN4O
Molecular Weight	377.21 g/mol
Synonyms	5-[4-(2-Bromo-5-fluorophenoxy)piperidin-1-yl]pyrazine-2-carbonitrile; 5-(4-(2-Bromo-5-fluorophenoxy)piperidin-1-yl)pyrazine-2-carbonitrile; 1042428-54-5; 2-Cyano-5-[4-(2-bromo-5-fluorophenoxy)-1-piperidinyl]pyrazine; 5-(4-(2-Bromo-5-fluorophenoxy)piperidino)-2-pyrazinecarbonitrile
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. We adhere to a strict quality management system to guarantee batch-to-batch consistency, purity, and identity for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is likely light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.