Description

(3S,4As,8As)-n-(1,1-Dimethylethyl)Decahydro-2-[(2R,3R)-2-Hydroxy-3-[(3-Hydroxy-2-Methylbenzoyl)Amino]-4-(Phenylsulfonyl)Butyl]-3-Isoquinolinecarboxamide is a complex, high-purity synthetic organic compound with a defined stereochemistry, serving as a critical advanced intermediate in modern pharmaceutical research and development. Its intricate molecular architecture makes it a valuable building block for the synthesis of novel therapeutic agents, particularly in targeting specific biological pathways. This compound is essential for research organizations and pharmaceutical companies engaged in the discovery and process development of new drugs, especially within oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new drug candidates.
• Process Chemistry Development: Serves as a reference standard or a critical intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Biochemical Research: Potential use as a tool compound or a ligand in biochemical assays to study enzyme inhibition or receptor binding.
• Custom Synthesis: A starting point for the custom synthesis of more complex, target-specific molecules for client-directed research projects.

Basic Information

Product Name	(3S,4As,8As)-n-(1,1-Dimethylethyl)Decahydro-2-[(2R,3R)-2-Hydroxy-3-[(3-Hydroxy-2-Methylbenzoyl)Amino]-4-(Phenylsulfonyl)Butyl]-3-Isoquinolinecarboxamide
CAS No.	1041389-29-0
Molecular Formula	C32H45N3O6S
Molecular Weight	599.78 g/mol
Synonyms	tert-Butyl (3S,4aS,8aS)-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylsulfonyl)butyl]decahydroisoquinoline-3-carboxylate; Decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylsulfonyl)butyl]-N-(tert-butyl)-3-isoquinolinecarboxamide; (3S,4aS,8aS)-N-tert-Butyl-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylsulfonyl)butyl]decahydroisoquinoline-3-carboxamide; CAS 1041389-29-0
EINECS	Contact for details

Quality Control

Our (3S,4As,8As)-n-(1,1-Dimethylethyl)Decahydro-2-[(2R,3R)-2-Hydroxy-3-[(3-Hydroxy-2-Methylbenzoyl)Amino]-4-(Phenylsulfonyl)Butyl]-3-Isoquinolinecarboxamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the exacting standards required for pharmaceutical research. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.