Description

[1-(3-Furylmethyl)-3-Oxo-2-Piperazinyl]Acetic Acid is a specialized heterocyclic building block and pharmaceutical intermediate of significant interest in modern synthetic chemistry. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic pathways. Pharmaceutical R&D laboratories, fine chemical manufacturers, and contract research organizations (CROs) need this high-purity intermediate to accelerate their drug discovery and process development programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Protease Inhibitor Research: Used in the development of enzyme inhibitors, where the piperazinone core is a privileged scaffold.
• Peptidomimetic Chemistry: Acts as a constrained dipeptide analog in the design of bioactive peptides with enhanced stability and potency.
• Medicinal Chemistry & SAR Studies: Employed for structure-activity relationship (SAR) exploration to optimize lead compounds in drug discovery pipelines.
• Custom Synthesis & Scale-Up: Supplied for custom synthesis projects, from milligram-scale research to kilogram-scale process development under cGMP guidelines.
• Academic Research: Utilized in university and institutional labs for investigating new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	[1-(3-Furylmethyl)-3-Oxo-2-Piperazinyl]Acetic Acid
CAS No.	1038840-14-0
Molecular Formula	C11H14N2O4
Molecular Weight	238.24 g/mol
Synonyms	2-[(1-[(Furan-3-yl)methyl]-3-oxo-2-piperazinyl]acetic acid; 2-(1-(Furan-3-ylmethyl)-3-oxopiperazin-2-yl)acetic acid; 1-(3-Furanylmethyl)-3-oxo-2-piperazineacetic acid; (1-((Furan-3-yl)methyl)-3-oxo-2-piperazinyl)acetic acid; Furan-3-ylmethyl-piperazinone-acetic acid derivative; 1038840-14-0; 2-(1-(Furan-3-ylmethyl)-3-oxopiperazin-2-yl)ethanoic acid
EINECS	Contact for details

Quality Control

Our [1-(3-Furylmethyl)-3-Oxo-2-Piperazinyl]Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D and scale-up. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.