Description

1-(1H-Pyrrol-2-Ylcarbonyl)Piperazine (Hydrochloride Salt) is a high-purity, specialized organic building block crucial for advanced pharmaceutical research and development. This compound serves as a key intermediate in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and oncological pathways. It is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop new therapeutic candidates.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially in neurological and oncological research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new molecular entities.
• Process Chemistry Development: Serves as a key starting material or intermediate in the scale-up and optimization of API manufacturing routes.
• Bioconjugation & Probe Synthesis: Utilized in the development of chemical probes, biomarkers, and targeted drug delivery systems due to its reactive piperazine moiety.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for exploratory synthetic chemistry and bioassay development.

Basic Information

Product Name	1-(1H-Pyrrol-2-Ylcarbonyl)Piperazine (Hydrochloride Salt)
CAS No.	1038285-42-5
Molecular Formula	C9H14ClN3O
Molecular Weight	215.68 g/mol
Synonyms	1-(1H-Pyrrole-2-carbonyl)piperazine hydrochloride; 1-(1H-Pyrrol-2-ylcarbonyl)piperazine HCl; Piperazine, 1-(1H-pyrrol-2-ylcarbonyl)-, hydrochloride (1:1); 1-Piperazinecarboxylic acid, 1H-pyrrol-2-yl-, monohydrochloride; 1038285-42-5; Pyrrole-2-carboxypiperazine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(1H-Pyrrol-2-Ylcarbonyl)Piperazine HCl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) to ensure traceability and compliance with your research or production standards. Custom synthesis and purification to meet specific pharmacopeial or internal specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.