Description

1-(Cyclopropylsulfonyl)Piperidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique sulfonyl-piperidine-carboxylic acid scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing novel bioactive molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of potential drug candidates, particularly in areas targeting central nervous system (CNS) disorders and other therapeutic applications.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Synthesis: The sulfonyl and carboxylic acid functionalities make it a candidate for constructing protease inhibitor scaffolds.
• Ligand Development for CNS Targets: The piperidine core is a common motif in ligands for G-protein coupled receptors (GPCRs) relevant to neurological conditions.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing of complex, high-value organic molecules.
• Academic & Industrial Research: Serves as a reagent in chemical biology and organic synthesis research within universities and corporate R&D labs.

Basic Information

Product Name	1-(Cyclopropylsulfonyl)Piperidine-4-Carboxylic Acid
CAS No.	1036738-97-2
Molecular Formula	C9H15NO4S
Molecular Weight	233.29 g/mol
Synonyms	1-(Cyclopropylsulfonyl)piperidine-4-carboxylic acid; 4-Piperidinecarboxylic acid, 1-(cyclopropylsulfonyl)-; Piperidine-4-carboxylic acid, 1-(cyclopropylsulfonyl)-; 1-Cyclopropylsulfonyl-piperidine-4-carboxylic acid; 1-(Cyclopropylsulfonyl)azepane-4-carboxylic acid (alternative ring naming); Cyclopropanesulfonic acid piperidin-4-ylamide derivative; CPSCA (abbreviation); 1036738-97-2
EINECS	Contact for details

Quality Control

Our 1-(Cyclopropylsulfonyl)Piperidine-4-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and other relevant analytical techniques. Our quality commitment aligns with cGMP principles where applicable for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.