Description

4-(4-Methylpiperazin-1-Yl)-2-[(Tetrahydropyran-4-Yl)(2,2,2-Trifluoroacetyl)Amino]Benzoic Acid Trifluoroacetate is a high-purity, advanced pharmaceutical intermediate with a complex molecular architecture designed for targeted synthesis. This compound matters as a critical building block in modern medicinal chemistry, enabling the development of novel therapeutic agents with enhanced specificity and efficacy. It is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and process development of new drugs, particularly in oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs) for clinical research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Process Chemistry Development: Serves as a standard or reference material for scaling up and optimizing synthetic routes in pilot plants.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for the custom synthesis of complex molecules under GMP or non-GMP conditions.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and heterocyclic chemistry.
• Library Synthesis: Employed in the generation of focused chemical libraries for high-throughput screening against biological targets.

Basic Information

Product Name	4-(4-Methylpiperazin-1-Yl)-2-[(Tetrahydropyran-4-Yl)(2,2,2-Trifluoroacetyl)Amino]Benzoic Acid Trifluoroacetate
CAS No.	1034975-62-6
Molecular Formula	C20H25F6N3O5
Molecular Weight	501.42 g/mol
Synonyms	4-(4-Methylpiperazin-1-yl)-2-[(tetrahydro-2H-pyran-4-yl)(2,2,2-trifluoroacetyl)amino]benzoic acid trifluoroacetate; 2-[(Tetrahydropyran-4-yl)(2,2,2-trifluoroacetyl)amino]-4-(4-methyl-1-piperazinyl)benzoic acid trifluoroacetate; Benzoic acid, 4-(4-methyl-1-piperazinyl)-2-[(tetrahydro-2H-pyran-4-yl)(2,2,2-trifluoroacetyl)amino]-, 2,2,2-trifluoroacetate (1:1); CAS 1034975-62-6
EINECS	Contact for details

Quality Control

Our 4-(4-Methylpiperazin-1-Yl)-2-[(Tetrahydropyran-4-Yl)(2,2,2-Trifluoroacetyl)Amino]Benzoic Acid Trifluoroacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.