Description

tert-Butyl 2-Amino-4-(4-Methylpiperazin-1-Yl)Benzoate is a high-purity, advanced pharmaceutical intermediate with a distinct molecular architecture. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Organic Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the construction of novel chemical libraries for high-throughput screening.
• Research & Development (R&D): Essential for academic and industrial R&D labs focusing on the development of new pharmacophores containing piperazine and benzoate motifs.
• API Manufacturing: Employed in the scaled-up production of active pharmaceutical ingredients that require the specific 2-amino-4-(4-methylpiperazin-1-yl)benzoate scaffold.
• Contract Manufacturing (CMO/CDMO): Supplied to contract manufacturing organizations that require reliable, high-quality intermediates for client-specified synthesis projects.

Basic Information

Product Name	tert-Butyl 2-Amino-4-(4-Methylpiperazin-1-Yl)Benzoate
CAS No.	1034975-35-3
Molecular Formula	C16H25N3O2
Molecular Weight	291.39 g/mol
Synonyms	2-Amino-4-(4-methyl-1-piperazinyl)benzoic acid 1,1-dimethylethyl ester; Benzoic acid, 2-amino-4-(4-methyl-1-piperazinyl)-, 1,1-dimethylethyl ester; tert-Butyl 2-amino-4-(4-methylpiperazin-1-yl)benzoate; 1034975-35-3; 4-(4-Methylpiperazin-1-yl)-2-aminobenzoic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Amino-4-(4-Methylpiperazin-1-Yl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.