Description

{3-Oxo-1-[3-(Trifluoromethyl)Benzyl]-2-Piperazinyl}Acetic Acid is a high-purity, non-natural amino acid derivative and a key synthetic intermediate of significant interest in advanced pharmaceutical research and development. Its molecular architecture, featuring a piperazine core and a trifluoromethylbenzyl group, makes it a valuable building block for constructing complex bioactive molecules. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel drug candidates, particularly in areas targeting the central nervous system and metabolic diseases.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential active pharmaceutical ingredients (APIs), especially for neurological and psychiatric disorders.
• Protease Inhibitor Research: Used as a scaffold or building block in the design and development of novel protease inhibitors due to its peptide-like structure.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization campaigns to explore new chemical entities.
• Chemical Biology: Acts as a tool compound or a labeled precursor for probing biological pathways and enzyme functions.
• Custom Synthesis: Provided to contract research and manufacturing organizations (CROs/CMOs) for client-specific custom synthesis projects.
• Academic Research: Supplied to university laboratories and research institutes for fundamental studies in organic synthesis and drug discovery.

Basic Information

Product Name	{3-Oxo-1-[3-(Trifluoromethyl)Benzyl]-2-Piperazinyl}Acetic Acid
CAS No.	1033600-26-8
Molecular Formula	C14H15F3N2O3
Molecular Weight	316.28 g/mol
Synonyms	2-[(3-Oxo-1-{[3-(trifluoromethyl)phenyl]methyl}piperazin-2-yl)acetic acid]; 1-[(3-Trifluoromethyl)benzyl]-3-oxo-2-piperazineacetic acid; (3-Oxo-1-{[3-(trifluoromethyl)phenyl]methyl}piperazin-2-yl)acetic acid; 2-(3-Oxo-1-((3-(trifluoromethyl)benzyl))-2-piperazinyl)acetic acid; 1-(3-(Trifluoromethyl)benzyl)-3-oxopiperazine-2-acetic acid; 1033600-26-8 (CAS Name based)
EINECS	Contact for details

Quality Control

Our {3-Oxo-1-[3-(Trifluoromethyl)Benzyl]-2-Piperazinyl}Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.