Description

[1-(2,2-Diphenyl-Ethyl)-3-Oxo-Piperazin-2-Yl]-Acetic Acid is a high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. Its complex piperazinone-acetic acid structure makes it a valuable building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system. This compound is essential for medicinal chemists and process development scientists in pharmaceutical and biotechnology companies seeking to develop new drug candidates with specific pharmacological profiles.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and neurological disorder targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic molecules.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized APIs and reference standards.
• Biochemical Research: Potential use as a tool compound or precursor in biochemical assays and proteomics research.

Basic Information

Product Name	[1-(2,2-Diphenyl-Ethyl)-3-Oxo-Piperazin-2-Yl]-Acetic Acid
CAS No.	1033600-06-4
Molecular Formula	C20H22N2O3
Molecular Weight	338.40 g/mol
Synonyms	2-[(1-(2,2-Diphenylethyl)-3-oxopiperazin-2-yl]acetic acid; 1-(2,2-Diphenylethyl)-3-oxopiperazine-2-acetic acid; (1-(2,2-Diphenylethyl)-3-oxo-2-piperazinyl)acetic acid; 1033600-06-4; UNII-6Q2Y8Y9Q3H; 6Q2Y8Y9Q3H
EINECS	Contact for details

Quality Control

Our [1-(2,2-Diphenyl-Ethyl)-3-Oxo-Piperazin-2-Yl]-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.