Description

4-(Hydroxymethyl)Piperidine-1-Carbonitrile is a versatile heterocyclic building block featuring both a hydroxymethyl and a nitrile functional group on a piperidine scaffold. This unique bifunctional structure makes it a valuable intermediate for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by medicinal chemists and process development scientists for constructing novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of central nervous system (CNS) drugs, enzyme inhibitors, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the piperidine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Material Science Research: Employed in the synthesis of novel polymers or functional materials where the nitrile and alcohol groups can be further modified.
• Chemical Biology Probes: Utilized to build molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	4-(Hydroxymethyl)Piperidine-1-Carbonitrile
CAS No.	1032824-91-1
Molecular Formula	C7H12N2O
Molecular Weight	140.19 g/mol
Synonyms	1-Cyano-4-(hydroxymethyl)piperidine; 4-Piperidinemethanol, 1-cyano-; 1-Cyano-4-piperidinemethanol; 4-(Hydroxymethyl)-1-piperidinecarbonitrile; 4-(Hydroxymethyl)piperidine-1-carbonitrile; Piperidine-1-carbonitrile, 4-(hydroxymethyl)-; 4-Hydroxymethylpiperidine-1-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-(Hydroxymethyl)Piperidine-1-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.