Description

2-Bromo-3,3,3-trifluoro-1-(4-methylpiperazin-1-yl)propan-1-one is a specialized fluorinated piperazine derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular architecture, featuring both bromine and trifluoromethyl groups, makes it a valuable precursor for introducing functional complexity into target molecules. This high-purity intermediate is primarily utilized by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Fluorinated Compound Research: Serves as a versatile precursor for introducing fluorine atoms into complex organic frameworks in academic and industrial R&D settings.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying biochemical pathways and protein interactions.
• Material Science Applications: Potential use in the synthesis of specialty polymers and advanced materials requiring specific fluorinated motifs.

Basic Information

Product Name	2-Bromo-3,3,3-trifluoro-1-(4-methylpiperazin-1-yl)propan-1-one
CAS No.	1031927-96-4
Molecular Formula	C8H10BrF3N2O
Molecular Weight	287.08 g/mol
Synonyms	1-(4-Methyl-1-piperazinyl)-2-bromo-3,3,3-trifluoro-1-propanone; 2-Bromo-3,3,3-trifluoro-1-(4-methyl-1-piperazinyl)-1-propanone; 2-Bromo-3,3,3-trifluoro-1-(4-methylpiperazin-1-yl)propan-1-one; 1031927-96-4; Propan-1-one, 2-bromo-3,3,3-trifluoro-1-(4-methyl-1-piperazinyl)-; 2-Bromo-3,3,3-trifluoro-1-(4-methylpiperazinyl)propan-1-one
EINECS	Contact for details

Quality Control

Our 2-Bromo-3,3,3-trifluoro-1-(4-methylpiperazin-1-yl)propan-1-one is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.