Description

3-Ethylpiperazine, N1-Cbz Protected is a key chiral intermediate and protected amine building block used in advanced organic synthesis. Its value lies in providing a selectively protected nitrogen atom on the piperazine ring, enabling precise and efficient construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the piperazine moiety contributes to biological activity.
• Peptidomimetic Chemistry: Serves as a constrained scaffold or a protected amine component in the design of peptide mimics and protease inhibitors.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for asymmetric catalysis and metal complexes.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up production under cGMP conditions.
• Academic & Industrial R&D: Used in research laboratories for methodological studies and the exploration of new chemical entities.

Basic Information

Product Name	3-Ethylpiperazine, N1-Cbz Protected
CAS No.	1031927-01-1
Molecular Formula	C14H20N2O2
Molecular Weight	248.32 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-3-ethylpiperazine; N-Carbobenzoxy-3-ethylpiperazine; 3-Ethyl-1-(phenylmethoxy)carbonylpiperazine; Cbz-3-Ethylpiperazine; 1-Cbz-3-Ethylpiperazine; N1-Cbz-3-Ethylpiperazine; 3-Ethylpiperazine-1-carboxylic acid benzyl ester; Benzyl 3-ethylpiperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 3-Ethylpiperazine, N1-Cbz Protected is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support development and commercial projects requiring compliance with cGMP, ICH guidelines, and other relevant regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.