Description

2-Ethylpiperazine, N1-Cbz Protected is a specialized, high-purity chemical intermediate featuring a carboxybenzyl (Cbz) protecting group on the piperazine nitrogen. This compound is critical for synthetic chemists as it enables the selective functionalization of the secondary amine in complex multi-step syntheses, particularly in pharmaceutical development. It is primarily utilized by research institutions and industrial R&D departments engaged in the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and sophisticated organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, particularly those containing piperazine or ethylpiperazine moieties.
• Peptide Chemistry: Used in the preparation of peptide analogs and mimetics where selective amine protection is required.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Employed in the creation of novel nitrogen-containing ligands for metal-catalyzed reactions.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects in CDMO (Contract Development and Manufacturing Organization) settings.
• Academic Research: Used in university and institutional labs for methodological studies in organic synthesis and protecting group chemistry.

Basic Information

Product Name	2-Ethylpiperazine, N1-Cbz Protected
CAS No.	1031927-00-0
Molecular Formula	C14H20N2O2
Molecular Weight	248.32 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-4-ethylpiperazine; N-Carbobenzyloxy-4-ethylpiperazine; 4-Ethyl-1-(phenylmethoxy)carbonylpiperazine; N1-Cbz-2-ethylpiperazine; Cbz-4-ethylpiperazine; 1-Cbz-4-ethylpiperazine; Benzyl 4-ethylpiperazine-1-carboxylate; Z-4-ethylpiperazine
EINECS	Contact for details

Quality Control

Our 2-Ethylpiperazine, N1-Cbz Protected is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.